Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae † †Electronic supplementary information (ESI) available: Experimental procedures and analytical data along with protocols for all biological experiments. See DOI: 10.1039/c4cc07003h Click here for additional data file.

Synthesis and stabilities of peptide-based [1]rotaxanes: molecular grafting onto lasso peptide scaffolds† †Electronic supplementary information (ESI) available: Experimental procedures and analytical data of all new compounds. CCDC 1520783. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00021a Click here for additional data file. Click here for additional data file.

Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae

Bacterial biofilms are surface associated bacterial communities of sessile cells encased in a matrix of polysaccharides, extracellular DNA and proteins. Such biofilms are of significant concern in nosocomial infections, where it is attributed to over $1 billion in increased hospital costs per annum in the US alone. Unlike cells in the planktonic state, bacterial biofilms do not exert their anti...

Spontaneous head-to-tail cyclization of unprotected linear peptides with the KAHA ligation† †Electronic supplementary information (ESI) available: Experimental procedures and analytical data of all new compounds. See DOI: 10.1039/c5sc01774b Click here for additional data file.

Stoichiometric to catalytic reactivity of the aryl cycloaurated species with arylboronic acids: insight into the mechanism of gold-catalyzed oxidative C(sp2)–H arylation† †Electronic supplementary information (ESI) available: Detailed experimental procedures, analytical data. CCDC 1000469, 1007212 and 1019879. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02070g Click here for additional data file. Click here for additional data file.

Photomodulation of bacterial growth and biofilm formation using carbohydrate-based surfactants† †Electronic supplementary information (ESI) available: Experimental procedures, supplementary tables, figures and spectra. See DOI: 10.1039/c6sc03020c Click here for additional data file.